Oxaprozin-d4
Based on 1 Customer Validation
Oxaprozin-d4 is the deuterium labeled Oxaprozin, which is a non-steroidal anti-inflammatory agent (NSAID).
For research use only. We do not sell to patients.
- Purity : 99.08%
- CAS No.: 2070015-11-9
- Formula: C18H11D4NO3
- Molecular Weight:297.34
-
Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biological Activity
-
Chemical Information
-
Solvent & Solubility
- Protocols
- Purity & Documentation
-
Help & FAQs
Biological Activity
Description
Application
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
-
CAS No. 2070015-11-9
-
Unlabeled CAS 21256-18-8
-
Appearance Solid
-
Molecular Weight 297.34
-
Formula C18H11D4NO3
-
Color White to off-white
-
SMILES
OC(C([2H])([2H])C([2H])([2H])C1=NC(C2=CC=CC=C2)=C(C3=CC=CC=C3)O1)=O
-
Synonyms
Wy-21743-d4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : ≥ 100 mg/mL (336.32 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Protocols
-
Research Protocol for Inflammation-related Diseases
The NLRP3 inflammasome is a cytosolic innate immune signaling platform that integrates priming signals and danger-signal activation to promote caspase-1 activation, maturation of IL-1β and IL-18, and gasdermin D-mediated pyroptotic cell death. The core experimental logic is to determine whether inflammatory disease phenotypes are driven by increased NLRP3 expression, ASC-containing inflammasome assembly, caspase-1 cleavage, GSDMD cleavage, and extracellular release of IL-1β/IL-18 rather than by nonspecific cell injury alone. The pathway is strongly linked to inflammation-related disease phenotypes because monosodium urate crystals activate NALP3/NLRP3 inflammasome signaling in gout-like crystal inflammation, cholesterol crystals activate NLRP3 inflammasomes in atherogenesis models, and DSS-induced intestinal inflammation has been reported to involve NLRP3 inflammasome activity. However, experimental colitis studies also show context-dependent protective effects of NLRP3 inflammasome co
Purity & Documentation
-
Data Sheet (249 KB)
-
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
-
Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3632 mL | 16.8158 mL | 33.6315 mL | 84.0788 mL |
| 5 mM | 0.6726 mL | 3.3632 mL | 6.7263 mL | 16.8158 mL | |
| 10 mM | 0.3363 mL | 1.6816 mL | 3.3632 mL | 8.4079 mL | |
| 15 mM | 0.2242 mL | 1.1211 mL | 2.2421 mL | 5.6053 mL | |
| 20 mM | 0.1682 mL | 0.8408 mL | 1.6816 mL | 4.2039 mL | |
| 25 mM | 0.1345 mL | 0.6726 mL | 1.3453 mL | 3.3632 mL | |
| 30 mM | 0.1121 mL | 0.5605 mL | 1.1211 mL | 2.8026 mL | |
| 40 mM | 0.0841 mL | 0.4204 mL | 0.8408 mL | 2.1020 mL | |
| 50 mM | 0.0673 mL | 0.3363 mL | 0.6726 mL | 1.6816 mL | |
| 60 mM | 0.0561 mL | 0.2803 mL | 0.5605 mL | 1.4013 mL | |
| 80 mM | 0.0420 mL | 0.2102 mL | 0.4204 mL | 1.0510 mL | |
| 100 mM | 0.0336 mL | 0.1682 mL | 0.3363 mL | 0.8408 mL |
Oxaprozin-d4 Related Classifications
HY-B0808S Related Classifications
Powered by Bioz