Arglabin (Standard)
Arglabin (Standard) is the analytical standard of Arglabin (HY-16059). This product is intended for research and analytical applications. Arglabin ((+)-Arglabin), a natural product isolated from Artemisia glabella, is a NLRP3 inflammasome inhibitor. Arglabin shows anti-inflammatory and antitumor activities. The antitumor activity of Arglabin proceeds through its inhibition of farnesyl transferase which leads to the activation of RAS proto-oncogene.
For research use only. We do not sell to patients.
- CAS No.: 84692-91-1
- Formula: C15H18O3
- Molecular Weight:246.30
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 84692-91-1
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Molecular Weight 246.30
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Formula C15H18O3
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SMILES
C[C@]12CC[C@]([H])([C@@]([H])([C@]3(C(C)=CC[C@]13O2)[H])OC4=O)C4=C
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Synonyms
(+)-Arglabin (Standard)
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Abderrazak A, et al. Anti-inflammatory and antiatherogenic effects of the NLRP3 inflammasome inhibitor arglabin in ApoE2.Ki mice fed a high-fat diet. Circulation. 2015;131(12):1061-1070. [Content Brief]
[2]. Lone SH, et al. Arglabin: From isolation to antitumor evaluation. Chem Biol Interact. 2015;240:180-198. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)