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Cat. No.: HY-175211

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BChE-IN-42

BChE-IN-42 (Compound 4a) is a BChE inhibitor with an IC₅₀ of 10.01 nM. BChE-IN-42 can be used for neurological diseases like Alzheimer's disease (AD) research.

For research use only. We do not sell to patients.

Formula: C₂₆H₂₆N₄O₆
Molecular Weight:490.51

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (272 KB)

BChE-IN-42 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

BChE-IN-42 (Compound 4a) is a BChE inhibitor with an IC₅₀ of 10.01 nM. BChE-IN-42 can be used for neurological diseases like Alzheimer's disease (AD) research^[1].

IC₅₀ & Target^[1]

BChE

10.01 nM (IC₅₀)

All Cholinesterase (ChE) Isoforms :

AChE
BChE

Chemical Information

Molecular Weight 490.51
Formula C₂₆H₂₆N₄O₆
SMILES

CC(OC(N1C(C=C2OC3=CC=CC=C3C(C2N1C(OC(C)C)=O)=O)C4=CN5C=CC=CC5=N4)=O)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (272 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Khalfaoui M, et al. Design, synthesis, and comprehensive evaluation of novel imidazole-chromone hybrids as potent cholinesterase and α-glucosidase inhibitors. Eur J Med Chem. 2025 Jul 3;297:117927. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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Amount: USD 0.00

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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BChE-IN-42

All Cholinesterase (ChE) Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

BChE-IN-42 Related Classifications

HY-175211 Related Classifications