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Cat. No.: HY-N19720

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Bractein

Bractein is a natural aurone flavonoid with potential antioxidant activity. Bractein shows in vitro antileishmanial activity and inhibits promastigotes and intracellular amastigotes of Leishmania donovani. Bractein exhibits no obvious cytotoxicity against mammalian macrophages with an EC₅₀ value > 25.0 μg/mL. Bractein can be used for the research of Leishmania.

For research use only. We do not sell to patients.

CAS No.: 22684-08-8
Formula: C₂₁H₂₀O₁₂
Molecular Weight:464.38

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Bractein Chemical Structure

CAS No.: 22684-08-8

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
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Biological Activity

Description

IC₅₀ & Target^[2]

Leishmania

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In Vitro

Bractein inhibits the growth of Leishmania donovani with an EC₅₀ value > 25.0 μg/mL^[2].
Bractein exhibits potential antioxidant properties, as evaluated via density functional theory (DFT) calculations^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 22684-08-8
Molecular Weight 464.38
Formula C₂₁H₂₀O₁₂
SMILES

O=C1/C(OC2=CC(O)=CC(O[C@H]3[C@@H]([C@H]([C@@H]([C@@H](CO)O3)O)O)O)=C12)=C/C4=CC(O)=C(O)C(O)=C4
Structure Classification
- Phenols
- Polyphenols
Initial Source
- Plants
- Compositae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Senthil Kumar K. A comparative study on the antioxidant properties of bractein and cernuoside by the DFT method. Monatsh Chem. 2013;144(10):1513-1524.

[2]. Kayser O, et al. In vitro leishmanicidal activity of aurones. Planta Med. 1999 May;65(4):316-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References

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Bractein

All Parasite Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Bractein Related Classifications

HY-N19720 Related Classifications