Fast-TRFS
Based on 2 publication(s) in Google Scholar
Fast-TRFS is a selective and superfast fluorogenic probe of thioredoxin reductase (TrxR). Fast-TRFS can be used for imaging TrxR activity in live cells.
For research use only. We do not sell to patients.
- Purity: 99.72%
- CAS No.: 2966536-18-3
- Formula: C14H11F3N2O3S2
- Molecular Weight:376.37
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Storage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Fast-TRFS
More
Biological Activity
Fast-TRFS reaches the maximal fluorescence signal within 1 min incubated with TCEP, and within 5 min incubated with the TrxR enzyme[1].
Fast-TRFS (10 μM; 2-60 min) appears the blue fluorescence signal within 2 min in HeLa cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Chemical Information
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CAS No. 2966536-18-3
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Appearance Solid
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Molecular Weight 376.37
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Formula C14H11F3N2O3S2
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Color White to light yellow
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SMILES
O=C1OC(C=C(C=C2)NC(NC3CSSC3)=O)=C2C(C(F)(F)F)=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Antioxidants (Basel)
2022 Feb 13;11(2):377. PMID: 35204259 -
Microbiol Resour Announc
Redox status and metabolomic profiling of thioredoxin reductase inhibitors and 4 kGy ionizing radiation-exposed Deinococcus radiodurans. [Abstract]2022 May 13;261:127070. PMID: 35623162
Solvent & Solubility
DMSO : 100 mg/mL (265.70 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.6570 mL | 13.2848 mL | 26.5696 mL | 66.4240 mL |
| 5 mM | 0.5314 mL | 2.6570 mL | 5.3139 mL | 13.2848 mL | |
| 10 mM | 0.2657 mL | 1.3285 mL | 2.6570 mL | 6.6424 mL | |
| 15 mM | 0.1771 mL | 0.8857 mL | 1.7713 mL | 4.4283 mL | |
| 20 mM | 0.1328 mL | 0.6642 mL | 1.3285 mL | 3.3212 mL | |
| 25 mM | 0.1063 mL | 0.5314 mL | 1.0628 mL | 2.6570 mL | |
| 30 mM | 0.0886 mL | 0.4428 mL | 0.8857 mL | 2.2141 mL | |
| 40 mM | 0.0664 mL | 0.3321 mL | 0.6642 mL | 1.6606 mL | |
| 50 mM | 0.0531 mL | 0.2657 mL | 0.5314 mL | 1.3285 mL | |
| 60 mM | 0.0443 mL | 0.2214 mL | 0.4428 mL | 1.1071 mL | |
| 80 mM | 0.0332 mL | 0.1661 mL | 0.3321 mL | 0.8303 mL | |
| 100 mM | 0.0266 mL | 0.1328 mL | 0.2657 mL | 0.6642 mL |
Fast-TRFS Related Classifications
HY-D1252 Related Classifications
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