MAI-400
MAI-400 is an APC-Asef interaction inhibitor (Kd = 12 nM, IC50 = 250 nM). MAI-400 can be used in the research of colorectal cancer.
For research use only. We do not sell to patients.
- CAS No.: 2250328-65-3
- Formula: C41H56N8O15
- Molecular Weight:900.93
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
Kd = 12 nM, IC50 = 250 nM (APC-Asef interaction)[1]
Chemical Information
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CAS No. 2250328-65-3
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Molecular Weight 900.93
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Formula C41H56N8O15
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SMILES
O=C(O)CC[C@@H](C(N)=O)NC([C@H](CC1=CC=C(O)C=C1)NC([C@H](CC(C)C)NC([C@H](CO)NC([C@@H](NC(CNC([C@@H](NC(OCC2=CC=CC=C2)=O)C)=O)=O)CCC(O)=O)=O)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)