Myrianthic acid
Based on 1 Customer Validation
Myrianthic acid is a pentacyclic triterpenoid compound. Myrianthic acid can exist in the root wood of Myrianthus arboreus and the leaves of Campsis grandiflora. Myrianthic acid inhibits adrenaline-induced platelet aggregation, with a IC50 of 46.2 μM for this activity. Myrianthic acid can be used in studies related to thrombosis.
For research use only. We do not sell to patients.
- Purity: 98.0%
- CAS No.: 89786-84-5
- Formula: C30H48O6
- Molecular Weight:504.70
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Storage:
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| RAW264.7 | IC50 |
10.38 μM
Compound: 12
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-10 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
| RAW264.7 | IC50 |
14.32 μM
Compound: 12
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced TNF-alpha release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
| RAW264.7 | IC50 |
8.04 μM
Compound: 12
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-6 release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
| RAW264.7 | IC50 |
8.53 μM
Compound: 12
|
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
Antiinflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced IL-1beta release incubated for 4 hrs prior to LPS challenge measured after 24 hrs by ELISA
|
[PMID: 23632365] |
Myrianthic acid inhibits adrenaline-induced platelet aggregation, with an IC50 of 46.2 μM for this activity[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 89786-84-5
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Appearance Solid
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Molecular Weight 504.70
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Formula C30H48O6
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Color White to off-white
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SMILES
OC([C@]12[C@]([C@](O)([C@@H](CC2)C)C)([H])C3=CC[C@@]([C@@]4([C@@]([C@@](C)([C@@H]([C@@H](C4)O)O)CO)([H])CC5)C)([H])[C@]5(C)[C@@]3(CC1)C)=O
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Structure Classification
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Initial Source
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
-20°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Myrianthic acid
- 89786-84-5
- Others
- epinephrine-induced platelet aggregation
- pentacyclic triterpene acid
- thrombosis
- Campsis grandiflora
- collagen-induced platelet aggregation
- arachidonic acid-induced platelet aggregation
- rat platelet-rich plasma
- ADP-induced platelet aggregation
- U46619-induced platelet aggregation
- Myrianthus arboreus
- Inhibitor
- inhibitor
- inhibit