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Cat. No.: HY-105537

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Ro 70‐0004

(Synonyms: RS-100975)

Ro 70-0004 (RS-100975) is a selective alpha1A-adrenoceptor antagonist with a pK_i of 8.9. Ro 70‐0004 can be used in the study of prostatic hyperplasia.

For research use only. We do not sell to patients.

CAS No.: 186386-21-0
Formula: C₂₀H₂₄F₄N₄O₃
Molecular Weight:444.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Ro 70‐0004 Chemical Structure

CAS No.: 186386-21-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
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Biological Activity

Description

Ro 70-0004 (RS-100975) is a selective alpha1A-adrenoceptor antagonist with a pK_i of 8.9. Ro 70‐0004 can be used in the study of prostatic hyperplasia^[1].

IC₅₀ & Target

Alpha-1A adrenergic receptor

8.9 (pKi)

All Adrenergic Receptor Isoforms :

Chemical Information

CAS No. 186386-21-0
Molecular Weight 444.42
Formula C₂₀H₂₄F₄N₄O₃
SMILES

O=C1NC=C(C)C(N1CCCN2CCN(CC2)C3=CC=C(C=C3OCC(F)(F)F)F)=O
Synonyms

RS-100975
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Williams TJ, et al. In vitro alpha1-adrenoceptor pharmacology of Ro 70-0004 and RS-100329, novel alpha1A-adrenoceptor selective antagonists. Br J Pharmacol. 1999 May;127(1):252-8. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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Ro 70‐0004

All Adrenergic Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Ro 70‐0004 Related Classifications

HY-105537 Related Classifications