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Cat. No.: HY-105829

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Sulfatroxazole

(Synonyms: Isosulfafurazole)

Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC₅₀=0.26 μM).

For research use only. We do not sell to patients.

CAS No.: 23256-23-7
Formula: C₁₁H₁₃N₃O₃S
Molecular Weight:267.30

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

Sulfatroxazole Chemical Structure

CAS No.: 23256-23-7

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

Sulfatroxazole (Isosulfafurazole) (compound 12) is a selective antagonist of ETA receptor (IC₅₀=0.26 μM)^[1].

All Endothelin Receptor Isoforms :

ET_A
ET_B

Cellular Effect

Cell Line	Type	Value	Description	References
A7R5	IC₅₀	5 μM Compound: 5d	Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptor Displacement of [125 I] ET-1 from rat aortic smooth muscle A7r5 cells transfected with Endothelin A receptor	[PMID: 10969989]

Chemical Information

CAS No. 23256-23-7
Molecular Weight 267.30
Formula C₁₁H₁₃N₃O₃S
SMILES

O=S(NC1=NOC(C)=C1C)(C2=CC=C(C=C2)N)=O
Synonyms

Isosulfafurazole
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Stein P D, et al. Discovery and structure-activity relationships of sulfonamide ETA-selective antagonists[J]. Journal of medicinal chemistry, 1995, 38(8): 1344-1354. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
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Sulfatroxazole

High-Throughput Bioactive Compound Library

All Endothelin Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Sulfatroxazole Related Classifications

HY-105829 Related Classifications