1. Antibody-drug Conjugate/ADC Related
  2. Drug-Linker Conjugates for ADC
  3. DL-01

DL-01 is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs.

For research use only. We do not sell to patients.

DL-01 Chemical Structure

DL-01 Chemical Structure

CAS No. : 2821770-49-2

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1 mg USD 880 Ask For Quote & Lead Time
5 mg USD 2200 Ask For Quote & Lead Time

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Description

DL-01 is a drug-linker conjugates for ADC that can be used for the synthesis of ADCs[1].

Molecular Weight

1098.27

Formula

C55H71N9O13S

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

CS(C1=NC=C(C=N1)C#CCCCC(N[C@@H](C(C)C)C(N[C@@H](CCCCN(CCC)CCC)C(NCC(NCOCCCC2=C3C(C(N4C3)=CC([C@](O)(C(OC5)=O)CC)=C5C4=O)=NC6=CC(OCO7)=C7C=C62)=O)=O)=O)=O)(=O)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (91.05 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 0.9105 mL 4.5526 mL 9.1052 mL
5 mM 0.1821 mL 0.9105 mL 1.8210 mL
View the Complete Stock Solution Preparation Table
  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration
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Volume
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Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
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Calculation results:
Working solution concentration: mg/mL
Purity & Documentation
References

Complete Stock Solution Preparation Table

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 0.9105 mL 4.5526 mL 9.1052 mL 22.7631 mL
5 mM 0.1821 mL 0.9105 mL 1.8210 mL 4.5526 mL
10 mM 0.0911 mL 0.4553 mL 0.9105 mL 2.2763 mL
15 mM 0.0607 mL 0.3035 mL 0.6070 mL 1.5175 mL
20 mM 0.0455 mL 0.2276 mL 0.4553 mL 1.1382 mL
25 mM 0.0364 mL 0.1821 mL 0.3642 mL 0.9105 mL
30 mM 0.0304 mL 0.1518 mL 0.3035 mL 0.7588 mL
40 mM 0.0228 mL 0.1138 mL 0.2276 mL 0.5691 mL
50 mM 0.0182 mL 0.0911 mL 0.1821 mL 0.4553 mL
60 mM 0.0152 mL 0.0759 mL 0.1518 mL 0.3794 mL
80 mM 0.0114 mL 0.0569 mL 0.1138 mL 0.2845 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
DL-01
Cat. No.:
HY-155870
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