1. Cell Cycle/DNA Damage
  2. Nucleoside Antimetabolite/Analog
  3. Dmf-dg

Dmf-dg  (Synonyms: 2'-Deoxy-N2-dimethylaminomethylene-guanosine)

Cat. No.: HY-W098689 Purity: 98.0%
Handling Instructions Technical Support

Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis.

For research use only. We do not sell to patients.

Dmf-dg

Dmf-dg Chemical Structure

CAS No. : 17331-13-4

Size Price Stock Quantity
Solid + Solvent (Highly Recommended)
10 mM * 1 mL in DMSO
ready for reconstitution
In-stock
Solution
10 mM * 1 mL in DMSO In-stock
Solid
500 mg In-stock
1 g In-stock
5 g   Get quote  
10 g   Get quote  

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Description

Dmf-dg (2'-Deoxy-N2-dimethylaminomethylene-guanosine) is a deoxyguanosine (dG) nucleoside protected by the dimethylaminomethylamidine (DMF) base and can be used for oligonucleotide synthesis[1].

Molecular Weight

322.32

Formula

C13H18N6O4

CAS No.
Appearance

Solid

Color

White to off-white

SMILES

OC1=C2C(N([C@H]3C[C@H](O)[C@@H](CO)O3)C=N2)=NC(/N=C/N(C)C)=N1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

4°C, protect from light, stored under nitrogen

*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen)

Solvent & Solubility
In Vitro: 

DMSO : 12.5 mg/mL (38.78 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.1025 mL 15.5125 mL 31.0251 mL
5 mM 0.6205 mL 3.1025 mL 6.2050 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 98.0%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light, stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 3.1025 mL 15.5125 mL 31.0251 mL 77.5627 mL
5 mM 0.6205 mL 3.1025 mL 6.2050 mL 15.5125 mL
10 mM 0.3103 mL 1.5513 mL 3.1025 mL 7.7563 mL
15 mM 0.2068 mL 1.0342 mL 2.0683 mL 5.1708 mL
20 mM 0.1551 mL 0.7756 mL 1.5513 mL 3.8781 mL
25 mM 0.1241 mL 0.6205 mL 1.2410 mL 3.1025 mL
30 mM 0.1034 mL 0.5171 mL 1.0342 mL 2.5854 mL
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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Dmf-dg
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