DPP-4/GPR119 modulator 1
DPP-4/GPR119 modulator 1 (Compound 22) is an orally active dipeptidyl peptidase IV (DPP-IV) inhibitor and GPR119 agonist. DPP-4/GPR119 modulator 1 shows blood glucose-lowering effect and moderate inhibition on hERG channel with an IC50 of 4.9 μM. DPP-4/GPR119 modulator 1 can be used for diabetes research. DPP-4/GPR119 modulator 1 is a click chemistry reagent, it contains an Alkyne group and can undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing Azide groups.
For research use only. We do not sell to patients.
- CAS No.: 2411099-68-6
- Formula: C30H39ClN10O3
- Molecular Weight:623.15
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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DPP-4 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Vero | IC50 |
>64 μg/mL
Compound: 22; HBK001-HCl
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Cytotoxicity against African green monkey Vero cells incubated for 48 hrs by MTT assay
Cytotoxicity against African green monkey Vero cells incubated for 48 hrs by MTT assay
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[PMID: 31926470] |
Chemical Information
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CAS No. 2411099-68-6
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Molecular Weight 623.15
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Formula C30H39ClN10O3
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SMILES
CC#CCN1C(N2CCC[C@H](C2)N)=NC3=C1C(N(C(N3C)=O)CCCN4CCN(CC4)C5=NC(C6=CC=CC=C6)=NO5)=O.Cl
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
DPP-4/GPR119 modulator 1 Related Classifications
HY-146468 Related Classifications
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