DSG-PEG2000-LTLRWVGLMS
DSG-PEG2000-LTLRWVGLMS (DSG-PEG2000-Mal-Cys-LTLRWVGLMS) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an LTLRWVGLMS peptide as a terminal targeting/functional ligand. DSG-PEG2000-LTLRWVGLMS can be used in research on targeted drug delivery for gliomas.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
In Vitro
DSG-PEG2000-LTLRWVGLMS is composed of three covalently linked components: 1. DSG (distearoylglycerol) : Lipid anchoring group-a diacylglycerol with two saturated C18 chains; provides strong membrane rigidity and sustained nanoparticle stability, suitable for applications requiring prolonged circulation time. 2. PEG 2000 (polyethylene glycol, molecular weight 2000): Hydrophilic polymer spacer arm-forms a steric hindrance crown around nanoparticles, reducing opsonin activity and reticuloendothelial system (RES) clearance, prolonging circulating half-life, and providing steric separation between the lipid surface and the targeting ligand. 3. LTLRWVGLMS peptide: Targeting/functional ligand-LTLRWVGLMS peptide is a glioma homing peptide that selectively binds to glioma cells, achieving targeted delivery to gliomas.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
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SMILES
[DSG-PEG2000-LTLRWVGLMS]
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Synonyms
DSG-PEG2000-Mal-Cys-LTLRWVGLMS
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)