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製品番号: HY-189171A

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DSG-PEG2000-LTLRWVGLMS

Name: DSG-PEG2000-LTLRWVGLMS
Brand: MedChemExpress
SKU: HY-189171A
Availability: PreOrder

(別名: DSG-PEG2000-Mal-Cys-LTLRWVGLMS)

DSG-PEG2000-LTLRWVGLMS (DSG-PEG2000-Mal-Cys-LTLRWVGLMS) is a functionalized PEGylated phospholipid conjugate composed of three modular components: distearoylglycerol (DSG) as a lipid anchoring group, a 2000 Da polyethylene glycol (PEG) spacer arm, and an LTLRWVGLMS peptide as a terminal targeting/functional ligand. DSG-PEG2000-LTLRWVGLMS can be used in research on targeted drug delivery for gliomas.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

DSG-PEG2000-LTLRWVGLMS 構造式

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

DSG-PEG2000-LTLRWVGLMS is composed of three covalently linked components: 1. DSG (distearoylglycerol) : Lipid anchoring group-a diacylglycerol with two saturated C18 chains; provides strong membrane rigidity and sustained nanoparticle stability, suitable for applications requiring prolonged circulation time. 2. PEG 2000 (polyethylene glycol, molecular weight 2000): Hydrophilic polymer spacer arm-forms a steric hindrance crown around nanoparticles, reducing opsonin activity and reticuloendothelial system (RES) clearance, prolonging circulating half-life, and providing steric separation between the lipid surface and the targeting ligand. 3. LTLRWVGLMS peptide: Targeting/functional ligand-LTLRWVGLMS peptide is a glioma homing peptide that selectively binds to glioma cells, achieving targeted delivery to gliomas.

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

SMILES

[DSG-PEG2000-LTLRWVGLMS]
別名

DSG-PEG2000-Mal-Cys-LTLRWVGLMS
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Laakkonen P, et al. Homing peptides as targeted delivery vehicles. Integr Biol (Camb). 2010 Aug;2(7-8):326-37. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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