DX3-235
Based on 1 Customer Validation
DX3-235 is an oxidative phosphorylation (OXPHOS) inhibitor. DX3-235 shows nanomolar inhibition of complex I function and ATP production in a galactose-containing medium resulting in significant cytotoxicity.
For research use only. We do not sell to patients.
- Purity: 99.97%
- CAS No.: 2749555-39-1
- Formula: C26H39N5O6S2
- Molecular Weight:581.75
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BXPC-3 | IC50 |
0.12 μM
Compound: 63
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Cytotoxicity against human BXPC-3 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
Cytotoxicity against human BXPC-3 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
|
[PMID: 34982568] |
| MIA PaCa-2 | IC50 |
0.05 μM
Compound: 63
|
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
Cytotoxicity against human MIA PaCa-2 cells assessed as inhibition of cell growth incubated for 7 days in glucose-containing medium by MTT assay
|
[PMID: 34982568] |
Chemical Information
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CAS No. 2749555-39-1
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Appearance Solid
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Molecular Weight 581.75
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Formula C26H39N5O6S2
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Color White to off-white
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SMILES
CC(C1=NOC(N2CCN(CC2)C([C@H]3CN(CCC3)S(=O)(C4=CC=C(C=C4)S(C(CC)CC)(=O)=O)=O)=O)=N1)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)