2. Others Cytoskeleton Apoptosis
  3. Reference Standards Dynamin Apoptosis
  4. Dynole 34-2 (Standard)

Dynole 34-2 (Standard) is the analytical standard of Dynole 34-2 (HY-107545). This product is intended for research and analytical applications. Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 µM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME).

For research use only. We do not sell to patients.

Dynole 34-2 (Standard)

Dynole 34-2 (Standard) Chemical Structure

CAS No. : 1128165-88-7

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Description

Dynole 34-2 (Standard) is the analytical standard of Dynole 34-2 (HY-107545). This product is intended for research and analytical applications. Dynole 34-2 is a potent dynamin GTPase inhibitor (IC50s=6.9 and 14.2 µM for dynamin1 and dynamin2 GTPase activity, respectively) with antimitotic effect. Dynole 34-2 induces apoptosis, as revealed by cell blebbing, DNA fragmentation, and PARP cleavage. Dynole 34-2 also potently inhibits receptor mediated endocytosis (RME)[1][2].

Molecular Weight

408.58

Formula

C25H36N4O
CAS No.
SMILES

N#C/C(C(NCCCCCCCC)=O)=C\C1=CN(CCCN(C)C)C2=C1C=CC=C2
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
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Dynole 34-2 (Standard) Related Classifications

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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

Dynole 34-2 (Standard)1128165-88-7Reference StandardsDynaminApoptosisInhibitorinhibitorinhibit

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