Dyrk1A-IN-7
Dyrk1a-in-7 (Compound 29) is a selective DYRK1A kinase inhibitor, and has good kinase selectivity for CLK1 kinase. The IC50 value of DYRK1A is 28 nM. For CLK2, Kd is 17.5 nM. Dyrk1a-in-7 can be used in the research of cancer, type Ⅱ diabetes and neurological diseases.
For research use only. We do not sell to patients.
- Formula: C19H13F3N4O
- Molecular Weight:370.33
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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DYRK1A 28 nM (IC50) |
Chemical Information
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Molecular Weight 370.33
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Formula C19H13F3N4O
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SMILES
CC1=C(N2N=C(C=CC2=N1)C3=CC=NC=C3)C4=CC(OC(F)(F)F)=CC=C4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)