(E)-Coniferyl alcohol
Based on 1 Customer Validation
(E)-Coniferyl alcohol is the isomer of Coniferyl alcohol. Coniferyl alcohol is an intermediate in biosynthesis of eugenol and of stilbenoids and coumarin. Coniferyl alcohol specifically inhibits fungal growth.
For research use only. We do not sell to patients.
- Purity: 99.62%
- CAS No.: 32811-40-8
- Formula: C10H12O3
- Molecular Weight:180.20
-
Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
|
Human Endogenous Metabolite |
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| A549 | IC50 |
85 μM
Compound: 39
|
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
Cytotoxicity against human A549 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| B16-4A5 | IC50 |
16.1 μM
Compound: 14
|
Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control
Antimelanogenic activity in theophylline-stimulated mouse B16-4A5 cells assessed as inhibition of melanogenesis after 72 hrs relative to control
|
[PMID: 27756508] |
| Col2 | IC50 |
>20 μg/mL
Compound: 10
|
Cytotoxicity against human Col2 cells
Cytotoxicity against human Col2 cells
|
[PMID: 14987058] |
| HUVEC | IC50 |
>20 μg/mL
Compound: 10
|
Cytotoxicity against HUVEC
Cytotoxicity against HUVEC
|
[PMID: 14987058] |
| KB | IC50 |
>20 μg/mL
Compound: 10
|
Cytotoxicity against human KB cells
Cytotoxicity against human KB cells
|
[PMID: 14987058] |
| LNCaP | IC50 |
>20 μg/mL
Compound: 10
|
Cytotoxicity against human LNCAP cells
Cytotoxicity against human LNCAP cells
|
[PMID: 14987058] |
| LoVo | IC50 |
64 μM
Compound: 39
|
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
Cytotoxicity against human LoVo cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| Lu1 | IC50 |
>20 μg/mL
Compound: 10
|
Cytotoxicity against human Lu1 cells
Cytotoxicity against human Lu1 cells
|
[PMID: 14987058] |
| PC-3 | IC50 |
84 μM
Compound: 39
|
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
Cytotoxicity against human PC3 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| SK-MEL-28 | IC50 |
>100 μM
Compound: 39
|
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay
Cytotoxicity against human SK-MEL-28 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
| U-373MG ATCC | IC50 |
97 μM
Compound: 39
|
Cytotoxicity against human U373 cells after 72 hrs by MTT assay
Cytotoxicity against human U373 cells after 72 hrs by MTT assay
|
[PMID: 21696954] |
Chemical Information
-
CAS No. 32811-40-8
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Appearance Solid
-
Molecular Weight 180.20
-
Formula C10H12O3
-
Color White to off-white
-
SMILES
OC1=CC=C(/C=C/CO)C=C1OC.[(E)]
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Structure Classification
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 125 mg/mL (693.67 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (270 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
[1]. Keeling CI, et al. New components of the honey bee (Apis mellifera L.) queen retinue pheromone. Proc Natl Acad Sci U S A. 2003 Apr 15;100(8):4486-91. [Content Brief]
[2]. König S, et al. Soluble phenylpropanoids are involved in the defense response of Arabidopsis against Verticillium longisporum. New Phytol. 2014 May;202(3):823-37. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 5.5494 mL | 27.7469 mL | 55.4939 mL | 138.7347 mL |
| 5 mM | 1.1099 mL | 5.5494 mL | 11.0988 mL | 27.7469 mL | |
| 10 mM | 0.5549 mL | 2.7747 mL | 5.5494 mL | 13.8735 mL | |
| 15 mM | 0.3700 mL | 1.8498 mL | 3.6996 mL | 9.2490 mL | |
| 20 mM | 0.2775 mL | 1.3873 mL | 2.7747 mL | 6.9367 mL | |
| 25 mM | 0.2220 mL | 1.1099 mL | 2.2198 mL | 5.5494 mL | |
| 30 mM | 0.1850 mL | 0.9249 mL | 1.8498 mL | 4.6245 mL | |
| 40 mM | 0.1387 mL | 0.6937 mL | 1.3873 mL | 3.4684 mL | |
| 50 mM | 0.1110 mL | 0.5549 mL | 1.1099 mL | 2.7747 mL | |
| 60 mM | 0.0925 mL | 0.4624 mL | 0.9249 mL | 2.3122 mL | |
| 80 mM | 0.0694 mL | 0.3468 mL | 0.6937 mL | 1.7342 mL | |
| 100 mM | 0.0555 mL | 0.2775 mL | 0.5549 mL | 1.3873 mL |