cIAP1 ligand 1
Based on 1 Customer Validation
cIAP1 ligand 1 is the LCL161 derivative based IAP ligand. cIAP1 ligand 1 can be connected to the ABL ligand for protein by a linker to form SNIPER. cIAP1 ligand 1 can be used in prostate cancer research.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit : 99.07%
- CAS. Nr.: 2095244-42-9
- Formel: C31H42N4O6S
- Molecular Weight:598.75
-
Speicherung:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Biologische Aktivität
-
Chemical Information
-
Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
-
Help & FAQs
-
HY-128837
Nutlin carboxylic acidMDM2 Ligand -
HY-103597
Thalidomide-O-COOHCereblon Ligand -
HY-41547
Thalidomide 4-fluorideLigands for E3 Ligase -
HY-111663
VL285VHL Ligand -
HY-125905
VH032-cyclopropane-FLigand for E3 Ligase -
HY-103596
Thalidomide-4-OHCereblon Ligand -
HY-120217
VH032VHL Ligand -
HY-125845
(S,R,S)-AHPCVHL Ligand -
HY-42424
(S,R,S)-AHPC-Me hydrochlorideLigands for E3 Ligase -
HY-103597R
Thalidomide-O-COOH (Standard)Reference Standard -
HY-101763A
(S,R,S)-AHPC monohydrochlorideVHL Ligand -
HY-112078
(S,R,S)-AHPC-MeLigands for E3 Ligase
Biologische Aktivität
Beschreibung
IC50 & Target
|
cIAP1 |
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
Chemical Information
-
CAS. Nr. 2095244-42-9
-
Appearance Solid
-
Molecular Weight 598.75
-
Formel C31H42N4O6S
-
Color White to off-white
-
SMILES
OC1=CC(C(C2=CSC([C@H]3N(CCC3)C([C@@H](NC([C@@H](N(C(OC(C)(C)C)=O)C)C)=O)C4CCCCC4)=O)=N2)=O)=CC=C1
-
Synonyms
E3 ligase Ligand 12
-
Versand
Room temperature in continental US; may vary elsewhere.
-
Speicherung
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Lösungsmittel & Löslichkeit
In Vitro:
DMSO : 100 mg/mL (167.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
-
Data Sheet (275 KB)
-
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
-
Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6701 mL | 8.3507 mL | 16.7015 mL | 41.7537 mL |
| 5 mM | 0.3340 mL | 1.6701 mL | 3.3403 mL | 8.3507 mL | |
| 10 mM | 0.1670 mL | 0.8351 mL | 1.6701 mL | 4.1754 mL | |
| 15 mM | 0.1113 mL | 0.5567 mL | 1.1134 mL | 2.7836 mL | |
| 20 mM | 0.0835 mL | 0.4175 mL | 0.8351 mL | 2.0877 mL | |
| 25 mM | 0.0668 mL | 0.3340 mL | 0.6681 mL | 1.6701 mL | |
| 30 mM | 0.0557 mL | 0.2784 mL | 0.5567 mL | 1.3918 mL | |
| 40 mM | 0.0418 mL | 0.2088 mL | 0.4175 mL | 1.0438 mL | |
| 50 mM | 0.0334 mL | 0.1670 mL | 0.3340 mL | 0.8351 mL | |
| 60 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6959 mL | |
| 80 mM | 0.0209 mL | 0.1044 mL | 0.2088 mL | 0.5219 mL | |
| 100 mM | 0.0167 mL | 0.0835 mL | 0.1670 mL | 0.4175 mL |
cIAP1 ligand 1 Related Classifications
HY-128808 Related Classifications
Powered by Bioz