2. Cell Cycle/DNA Damage Cytoskeleton Apoptosis
  3. Microtubule/Tubulin Apoptosis
  4. EAPB 02303

EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel (HY-B0015) at lower concentrations.

For research use only. We do not sell to patients.

EAPB 02303 Chemical Structure

EAPB 02303 Chemical Structure

CAS No. : 1958290-51-1

Size Price Stock Quantity
1 mg USD 150 In-stock
5 mg USD 450 In-stock
10 mg USD 720 In-stock
25 mg USD 1450 In-stock
50 mg USD 2350 In-stock
100 mg USD 3800 In-stock
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Based on 1 publication(s) in Google Scholar

EAPB 02303 Related Antibodies

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Description

EAPB 02303 is a microtubule-disrupting agent and inhibitor. EAPB 02303 induces mitosis arrest and impairment of spindle assembly. Thus, EAPB 02303 induces apoptosis and exhibits antitumor activity. EAPB 02303 also exhibits a potent synergy with Paclitaxel (HY-B0015) at lower concentrations[1].

Molecular Weight

306.32

Formula

C17H14N4O2
CAS No.
Appearance

Solid

Color

Light yellow to yellow

SMILES

OC(C=C1)=C(O)C=C1C2=CN=C3C(NC)=NC4=CC=CC=C4N32
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)

Solvent & Solubility
In Vitro: 

H2O : 30 mg/mL (97.94 mM; ultrasonic and warming and heat to 60°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.2646 mL 16.3228 mL 32.6456 mL
5 mM 0.6529 mL 3.2646 mL 6.5291 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

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In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).
Purity & Documentation
References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
H2O 1 mM 3.2646 mL 16.3228 mL 32.6456 mL 81.6140 mL
5 mM 0.6529 mL 3.2646 mL 6.5291 mL 16.3228 mL
10 mM 0.3265 mL 1.6323 mL 3.2646 mL 8.1614 mL
15 mM 0.2176 mL 1.0882 mL 2.1764 mL 5.4409 mL
20 mM 0.1632 mL 0.8161 mL 1.6323 mL 4.0807 mL
25 mM 0.1306 mL 0.6529 mL 1.3058 mL 3.2646 mL
30 mM 0.1088 mL 0.5441 mL 1.0882 mL 2.7205 mL
40 mM 0.0816 mL 0.4081 mL 0.8161 mL 2.0403 mL
50 mM 0.0653 mL 0.3265 mL 0.6529 mL 1.6323 mL
60 mM 0.0544 mL 0.2720 mL 0.5441 mL 1.3602 mL
80 mM 0.0408 mL 0.2040 mL 0.4081 mL 1.0202 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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EAPB 02303 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

EAPB 023031958290-51-1EAPB02303EAPB-02303Microtubule/TubulinApoptosisInhibitorinhibitorinhibit

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