eeAChE-IN-1
eeAChE-IN-1 is a potent eeAChE inhibitor with an IC50 value of 23 nM.
For research use only. We do not sell to patients.
- CAS No.: 2763366-27-2
- Formula: C27H30N6O5S
- Molecular Weight:550.63
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
Description
IC50 & Target
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AChE |
Chemical Information
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CAS No. 2763366-27-2
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Molecular Weight 550.63
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Formula C27H30N6O5S
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SMILES
NS(=O)(C1=CC=C(C=C1)N2C(CC(C2=O)NCCNCC(NC3=C4C=CC=CC4=NC5=C3CCCC5)=O)=O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
[1]. Javed MA, et al. Structural Modification, In Vitro, In Vivo, Ex Vivo, and In Silico Exploration of Pyrimidine and Pyrrolidine Cores for Targeting Enzymes Associated with Neuroinflammation and Cholinergic Deficit in Alzheimer's Disease. ACS Chem Neurosci. 2021 Nov 3;12(21):4123-4143. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)