EGFR/HER2-IN-2
EGFR/HER2-IN-2 (Compound ZINC35560729) is a dual inhibitor of EGFR and HER2 with IC50 values of 5.02 µM and 0.83 µM against EGFR and HER2, respectively.
For research use only. We do not sell to patients.
- CAS No.: 1215571-02-0
- Formula: C26H23N5O3
- Molecular Weight:453.49
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Description
IC50 & Target
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HER2 0.83 μM (IC50) |
EGFR 5.02 μM (IC50) |
Chemical Information
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CAS No. 1215571-02-0
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Molecular Weight 453.49
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Formula C26H23N5O3
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SMILES
COC1=CC=C(C2=NN=C(C3=NC(NCC4=CC=CC=C4OCC)=C5C=CC=CC5=N3)O2)C=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
EGFR/HER2-IN-2 Related Classifications
HY-115951 Related Classifications
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