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Cat. No.: HY-182410

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EGIS-9637

EGIS-9637 is a non-competitive AMPA antagonist and acylated dihydro-2,3-benzodiazepine class member.

For research use only. We do not sell to patients.

CAS No.: 220669-66-9
Formula: C₂₁H₂₂N₄O₃
Molecular Weight:378.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

EGIS-9637 Chemical Structure

CAS No.: 220669-66-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Bioz

Biological Activity

Description

EGIS-9637 is a non-competitive AMPA antagonist and acylated dihydro-2,3-benzodiazepine class member^[1].

IC₅₀ & Target^[1]

AMPA Receptor

All iGluR Isoforms :

In Vitro

EGIS-9637 (compound 44a) inhibits hippocampal field potentials and retinal spreading in hippocampal brain slices^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 220669-66-9
Molecular Weight 378.42
Formula C₂₁H₂₂N₄O₃
SMILES

O=C(N1N=C(C2=C(CC1C)C=C3OCOC3=C2)C4=CC=C(N)C=C4)NC5CC5
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Sólyom S, et al. Non-competitive AMPA antagonists of 2,3-benzodiazepine type. Curr Pharm Des. 2002;8(10):913-939. [Content Brief]

Calculators

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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