Elacridar-d4(Major)
Elacridar-d4(Major) is the deuterium labeled Elacridar (HY-50879). Elacridar is an orally active P-glycoprotein (Pgp) and breast cancer resistance protein (BCRP) inhibitor. Elacridar can be used to examine the influence of efflux transporters on agent distribution to brain and the research of cancer.
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- CAS. Nr.: 1189481-51-3
- Formel: C34H29D4N3O5
- Molecular Weight:567.67
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Speicherung:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biologische Aktivität
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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CAS. Nr. 1189481-51-3
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Unlabeled Cas 143664-11-3
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Appearance Solid
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Molecular Weight 567.67
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Formel C34H29D4N3O5
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Color Light yellow to yellow
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SMILES
O=C(NC1=CC=C(C([2H])(C([2H])(N2CCC(C=C(C(OC)=C3)OC)=C3C2)[2H])[2H])C=C1)C4=CC=CC5=C4NC6=C(C5=O)C=CC=C6OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Reinheit & Dokumentation
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)