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Cat. No.: HY-129714

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EMD 52297

EMD 52297 is a Renin inhibitor, with acute hemodynamic and hormonal effects. EMD 52297 also acts as an ACE inhibitor.

For research use only. We do not sell to patients.

CAS No.: 129049-51-0
Formula: C₃₉H₅₉N₁₁O₇
Molecular Weight:793.96

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

EMD 52297 Chemical Structure

CAS No.: 129049-51-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

EMD 52297 is a Renin inhibitor, with acute hemodynamic and hormonal effects. EMD 52297 also acts as an ACE inhibitor^[1]^[2].

Chemical Information

CAS No. 129049-51-0
Molecular Weight 793.96
Formula C₃₉H₅₉N₁₁O₇
SMILES

O=C(NC(CC1=CC=CC=C1)C(NC(CC2=CN=CN2)C(NC(C(CC(NC(C(CC)C)C(NCN3N=NC=N3)=O)=O)O)CC4CCCCC4)=O)=O)OC(C)(C)C
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Miriam T Rademaker, et al. Hemodynamic, hormonal, and renal effects of (pro)renin receptor blockade in experimental heart failure. Circ Heart Fail. 2012 Sep 1;5(5):645-52. [Content Brief]

[2]. Jürgen Maibaum, et al. Renin inhibitors as novel treatments for cardiovascular disease. Expert Opinion on Therapeutic Patents. Volume 13, 2003 - Issue 5.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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