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Cat. No.: HY-N7279

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Epiaschantin

(Synonyms: (+)-Epiaschantin)

Epiaschantin is an anticancer agent. Epiaschantin shows antiproliferative activity.

For research use only. We do not sell to patients.

CAS No.: 41689-50-3
Formula: C₂₂H₂₄O₇
Molecular Weight:400.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

Epiaschantin Chemical Structure

CAS No.: 41689-50-3

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Epiaschantin is an anticancer agent. Epiaschantin shows antiproliferative activity^[1].

Cellular Effect

Cell Line	Type	Value	Description	References
BXPC-3	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human BxPC3 cells after 48 hrs by SRB assay Anticancer activity against human BxPC3 cells after 48 hrs by SRB assay	[PMID: 14987061]
DU-145	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human DU145 cells after 48 hrs by SRB assay Anticancer activity against human DU145 cells after 48 hrs by SRB assay	[PMID: 14987061]
KM-20L2	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human KM20L2 cells after 48 hrs by SRB assay Anticancer activity against human KM20L2 cells after 48 hrs by SRB assay	[PMID: 14987061]
MCF7	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human MCF7 cells after 48 hrs by SRB assay Anticancer activity against human MCF7 cells after 48 hrs by SRB assay	[PMID: 14987061]
NCI-H460	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human NCI-H460 cells after 48 hrs by SRB assay Anticancer activity against human NCI-H460 cells after 48 hrs by SRB assay	[PMID: 14987061]
P388	ED₅₀	1.5 μg/mL Compound: 4	Anticancer activity against mouse P388 cells after 48 hrs Anticancer activity against mouse P388 cells after 48 hrs	[PMID: 14987061]
SF-268	ED₅₀	>10 μg/mL Compound: 4	Anticancer activity against human SF268 cells after 48 hrs by SRB assay Anticancer activity against human SF268 cells after 48 hrs by SRB assay	[PMID: 14987061]

In Vitro

Epiaschantin (compound 4) (0-10 µM) shows antiproliferative activity with ED₅₀ value of 1.5 µg/mL for P388 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 41689-50-3
Molecular Weight 400.42
Formula C₂₂H₂₄O₇
SMILES

COC1=C(OC)C(OC)=CC([C@@H]2OC[C@]3([H])[C@@H](C4=CC=C(OCO5)C5=C4)OC[C@@]32[H])=C1
Synonyms

(+)-Epiaschantin
Structure Classification
- Phenylpropanoids
- Lignans
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Pettit GR, et al. Antineoplastic agents. 522. Hernandia peltata (Malaysia) and Hernandia nymphaeifolia (Republic of Maldives). J Nat Prod. 2004 Feb;67(2):214-20. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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