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Cat. No.: HY-N8658

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Epinodosin

Epinodosin is a diterpenoid. Epinodosin has moderate cytotoxicity against HL-60 cells with IC₅₀ value of 10.4 μM. Epinodosin can be used for the research of inflammatory diseases.

For research use only. We do not sell to patients.

CAS No.: 20086-60-6
Formula: C₂₀H₂₆O₆
Molecular Weight:362.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (281 KB)

Epinodosin Chemical Structure

CAS No.: 20086-60-6

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

Epinodosin is a diterpenoid. Epinodosin has moderate cytotoxicity against HL-60 cells with IC₅₀ value of 10.4 μM. Epinodosin can be used for the research of inflammatory diseases^[1].

IC₅₀ & Target

IC50: 10.4 μM (HL-60 cells)^[1]

Cellular Effect

Cell Line	Type	Value	Description	References
A549	IC₅₀	>40 μM Compound: 10	Cytotoxicity against human A549 cells after 48 hrs by MTS assay Cytotoxicity against human A549 cells after 48 hrs by MTS assay	[PMID: 24219809]
A549	IC₅₀	2.1 μM Compound: 10	Cytotoxicity against human A549 cells after 48 hrs Cytotoxicity against human A549 cells after 48 hrs	[PMID: 19697926]
HepG2	IC₅₀	0.45 μM Compound: Epinodosin	Cytotoxicity against human HepG2 cells Cytotoxicity against human HepG2 cells	[PMID: 22483090]
HepG2	IC₅₀	1.62 μM Compound: 10	Cytotoxicity against human HepG2 cells after 48 hrs Cytotoxicity against human HepG2 cells after 48 hrs	[PMID: 19697926]
HL-60	IC₅₀	>40 μM Compound: 10	Cytotoxicity against human HL60 cells after 48 hrs by MTS assay Cytotoxicity against human HL60 cells after 48 hrs by MTS assay	[PMID: 24219809]
K562	IC₅₀	0.56 μM Compound: 10	Cytotoxicity against human K562 cells after 48 hrs Cytotoxicity against human K562 cells after 48 hrs	[PMID: 19697926]
MCF7	IC₅₀	>40 μM Compound: 10	Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay Cytotoxicity against human MCF7 cells after 48 hrs by MTS assay	[PMID: 24219809]
SMMC-7721	IC₅₀	>40 μM Compound: 10	Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay Cytotoxicity against human SMMC7721 cells after 48 hrs by MTS assay	[PMID: 24219809]
SW480	IC₅₀	>40 μM Compound: 10	Cytotoxicity against human SW480 cells after 48 hrs by MTS assay Cytotoxicity against human SW480 cells after 48 hrs by MTS assay	[PMID: 24219809]

In Vitro

Epinodosin (Compounds 3) exhibits moderate cytotoxicity against HL-60 cells with an IC₅₀ value of 10.4 μM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 20086-60-6
Molecular Weight 362.42
Formula C₂₀H₂₆O₆
SMILES

O[C@@H]1[C@@]([C@]2(C(C3=C)=O)C[C@H]3C1)([H])[C@@]([C@@](CC4)([H])OC2=O)(CO5)[C@](C4(C)C)([H])[C@@H]5O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
- Plants
- Labiatae
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (281 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Su-Ping Bai, et al. Two novel ent-kauranoid diterpenoids from Isodon japonica leaves. Planta Med. 2005 Aug;71(8):764-9. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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