Episterol
Episterol is an Ergosterol (HY-N0181) biosynthetic intermediate. Episterol replaces Ergosterol as the major sterol in Saccharomyces cerevisiae Δerg3 mutants, confers resistance to combined lethal and vacuole-disruptive actions of Amphotericin B (HY-B0221) and MC12 (HY-175024).
For research use only. We do not sell to patients.
- CAS No.: 474-68-0
- Formula: C28H46O
- Molecular Weight:398.68
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Episterol accumulation in Saccharomyces cerevisiae Δerg3 mutant cells eliminates the synergistic antifungal activity between Amphotericin B (HY-B0221) and MC12 (HY-175024), resulting in an indifferent drug interaction with an FIC index of 2.00[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 474-68-0
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Molecular Weight 398.68
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Formula C28H46O
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SMILES
C[C@@]12[C@](C=3[C@@]([C@]4(C)[C@@](CC3)(C[C@@H](O)CC4)[H])(CC1)[H])(CC[C@@]2([C@@H](CCC(C(C)C)=C)C)[H])[H]
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Structure Classification
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Initial Source
Saccharomyces cerevisiae
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Episterol Related Classifications
HY-N9464 Related Classifications
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