ERα degrader 5
ERα degrader 5 (Compound 40) is a selective, orally bioavailable estrogen receptor (ER) degrader (SERD) with an EC50 of 1.1 nM against ERα. ERα degrader 5 shows antitumor effect in vivo.
For research use only. We do not sell to patients.
- CAS No.: 2941268-96-6
- Formula: C29H25F4N3O2S
- Molecular Weight:555.59
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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ERα 1.1 nM (EC50) |
ERα 0.9 nM (IC50) |
ERβ 2.3 nM (IC50) |
ERα degrader 5 (Compound 40) shows antiproliferative activity with an IC50 of 1.0 nM against MCF-7[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2941268-96-6
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Molecular Weight 555.59
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Formula C29H25F4N3O2S
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SMILES
CC(F)(C1=C(C2=C(C3=CC=C4NN=CC4=C3S2)OC5=CC=C(C=C5)OC6CN(C6)CCCF)C=CC(F)=C1)F
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
ERα degrader 5 Related Classifications
HY-146267 Related Classifications
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