BML264
BML264 ((E)-N-(p-amylcinnamoyl) anthranilic acid) is an agonist for TREK-1. BML264 can be used to study diseases associated with TASK1 dysfunction.
For research use only. We do not sell to patients.
- CAS No.: 99196-74-4
- Formula: C21H23NO3
- Molecular Weight:337.41
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
28 μM
Compound: ACA
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Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay
Agonist activity at human TRPA1 expressed in HEK293 cells assessed as increase in calcium influx by Fluo-4-AM dye based fluorescence assay
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[PMID: 30878828] |
| HEK293 | IC50 |
1.7 μM
Compound: ACA
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Inhibition of human TRPM2 expressed in HEK293 cells assessed as inhibition of H2O2-induced intracellular calcium level by patch clamp technique
Inhibition of human TRPM2 expressed in HEK293 cells assessed as inhibition of H2O2-induced intracellular calcium level by patch clamp technique
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[PMID: 24304219] |
Chemical Information
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CAS No. 99196-74-4
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Molecular Weight 337.41
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Formula C21H23NO3
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SMILES
O=C(O)C1=CC=CC=C1NC(/C=C/C2=CC=C(CCCCC)C=C2)=O
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Synonyms
(E)-N-(p-Amylcinnamoyl) anthranilic acid
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
BML264 Related Classifications
HY-118628A Related Classifications
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