Icterogenin
Icterogenin is a selective inhibitor targeting the Bcl-XL/Bak BH3 domain peptide interaction and exhibits anti-leukemic activity. Icterogenin regulates protein interactions and affects tumor cell survival. Icterogenin is an oleanane-type triterpenoid compound that can be isolated from Lantana camara and is useful in the field of anti-tumor drug development.
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- No. CAS: 561-47-7
- Fòrmula: C35H52O6
- Peso molecular:568.78
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Help & FAQs
Actividad biológica
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Bcl-xL |
Icterogenin exhibits cytotoxicity against HL-60 human promyelocytic leukemia cells, with IC50 values ranging from 1.16 to 68.4 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 561-47-7
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Peso molecular 568.78
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Fòrmula C35H52O6
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SMILES
OC([C@@]([C@@H](C1)OC(/C(C)=C\C)=O)(CC[C@]23C)[C@](CC1(C)C)([H])C2=CC[C@@]4([H])[C@]3(CC[C@]([C@](C)5CO)([H])[C@@]4(CCC5=O)C)C)=O
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Structure Classification
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Initial Source
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Icterogenin Related Classifications
HY-N9826 Related Classifications
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