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Referencia número: HY-176408

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PHD2-IN-5

PHD2-IN-5 (compound 22) is a potent PHD2 inhibitor with an IC₅₀ of 0.82 μM. PHD2-IN-5 can be used in the study of renal anemia.

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No. CAS: 1262131-72-5
Fòrmula: C₉H₉ClN₄O₄
Peso molecular:272.65

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

PHD2-IN-5 Chemical Structure

No. CAS: 1262131-72-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Actividad biológica

Descripciòn

PHD2-IN-5 (compound 22) is a potent PHD2 inhibitor with an IC₅₀ of 0.82 μM. PHD2-IN-5 can be used in the study of renal anemia^[1].

Ver todos los productos específicos de isoformas HIF/HIF Prolyl-Hydroxylase :

Chemical Information

No. CAS 1262131-72-5
Peso molecular 272.65
Fòrmula C₉H₉ClN₄O₄
SMILES

OC1=C(C(NCC(O)=O)=O)C2=NC=NN2C=C1.Cl
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Ogoshi Y, et al. Lead Generation for a HIF Prolyl Hydroxylase Inhibitor: Discovery of (7-Hydroxy-[1, 2, 4] triazolo [1, 5-a] pyridine-8-carbonyl) glycine as a Lead Compound of Enarodustat[J]. ACS Medicinal Chemistry Letters, 2025.

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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PHD2-IN-5

Ver todos los productos específicos de isoformas HIF/HIF Prolyl-Hydroxylase

Actividad biológica

Descripciòn

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

PHD2-IN-5 Related Classifications

HY-176408 Related Classifications

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