Thapsigargicin
Thapsigargicin (Thapsigargicine) is a activator of mast cells and leukocytes. Thapsigargicin induces histamine release from rat peritoneal mast cells and human basophil leukocytes. Thapsigargicin increases the cytoplasmic free calcium level in intact human blood platelets.
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- No. CAS: 67526-94-7
- Fòrmula: C32H46O12
- Peso molecular:622.70
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Almacenamiento:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Actividad biológica
Descripciòn
Chemical Information
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No. CAS 67526-94-7
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Appearance Solid
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Peso molecular 622.70
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Fòrmula C32H46O12
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Color White to off-white
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SMILES
CC1=C2[C@]([C@](C)(C[C@@H]([C@]3([C@@]2([H])OC([C@]3(O)C)=O)O)OC(CCC)=O)OC(C)=O)([H])[C@@H]([C@H]1OC(/C(C)=C\C)=O)OC(CCCCC)=O
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Synonyms
Thapsigargicine
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Structure Classification
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Pureza y Documentación
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Ficha de datos (274 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Ali H, et al. The ability of thapsigargin and thapsigargicin to activate cells involved in the inflammatory response. Br J Pharmacol. 1985 Jul;85(3):705-12. [Content Brief]
[2]. Khairy H, Adjei G, Allen-Redpath K, Scott RH. Actions of ethanolamine on cultured sensory neurones from neonatal rats. Neurosci Lett. 2010;468(3):326-329. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)