ET receptor antagonist 3
ET receptor antagonist 3 (compound 17d) is an orally active ET receptor antagonist (IC50=0.26 nM), which can be used for research in pulmonary arterial hypertension (PAH). ET receptor antagonist 3 attenuates monocrotaline (HY-N0750) induced PAH in rat model.
For research use only. We do not sell to patients.
- Formula: C27H28N6O5S
- Molecular Weight:548.61
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
IC50: 0.26 nM (ET receptor)[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 548.61
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Formula C27H28N6O5S
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SMILES
O=S(C1=CC=CC=C1)(NC2=NC(C3=NC=CC=N3)=NC(OCC4N(C)CCC4)=C2OC5=CC=CC=C5OC)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)