Ethyl hydroxyacetate
Based on 1 Customer Validation
Ethyl hydroxyacetate is a PROTAC linker that can be used in the synthesis of PROTACs.
For research use only. We do not sell to patients.
- CAS No.: 623-50-7
- Formula: C4H8O3
- Molecular Weight:104.11
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Storage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
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Help & FAQs
All PROTAC Linkers Isoforms
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Biological Activity
Description
In Vitro
PROTACs contain two different ligands connected by a linker; one is a ligand for an E640 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 623-50-7
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Appearance Liquid
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Molecular Weight 104.11
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Formula C4H8O3
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Color Colorless to light yellow
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SMILES
O=C(OCC)CO
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Solvent & Solubility
In Vitro:
DMSO : 100 mg/mL (960.52 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (240 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 2 years; -20°C, 1 year. When stored at -80°C, please use it within 2 years. When stored at -20°C, please use it within 1 year.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 9.6052 mL | 48.0261 mL | 96.0523 mL | 240.1306 mL |
| 5 mM | 1.9210 mL | 9.6052 mL | 19.2105 mL | 48.0261 mL | |
| 10 mM | 0.9605 mL | 4.8026 mL | 9.6052 mL | 24.0131 mL | |
| 15 mM | 0.6403 mL | 3.2017 mL | 6.4035 mL | 16.0087 mL | |
| 20 mM | 0.4803 mL | 2.4013 mL | 4.8026 mL | 12.0065 mL | |
| 25 mM | 0.3842 mL | 1.9210 mL | 3.8421 mL | 9.6052 mL | |
| 30 mM | 0.3202 mL | 1.6009 mL | 3.2017 mL | 8.0044 mL | |
| 40 mM | 0.2401 mL | 1.2007 mL | 2.4013 mL | 6.0033 mL | |
| 50 mM | 0.1921 mL | 0.9605 mL | 1.9210 mL | 4.8026 mL | |
| 60 mM | 0.1601 mL | 0.8004 mL | 1.6009 mL | 4.0022 mL | |
| 80 mM | 0.1201 mL | 0.6003 mL | 1.2007 mL | 3.0016 mL | |
| 100 mM | 0.0961 mL | 0.4803 mL | 0.9605 mL | 2.4013 mL |
Ethyl hydroxyacetate Related Classifications
HY-Y0914 Related Classifications
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