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Cat. No.: HY-N21917

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Euphornin C

Euphornin C is a jatrophane- and lathyrane-type diterpenoid. Euphornin C exists in the whole plant of Euphorbia helioscopia and the seeds of Euphorbia lathyris. Euphornin C inhibits NO production.

For research use only. We do not sell to patients.

CAS No.: 90052-86-1
Formula: C₃₁H₄₀O₈
Molecular Weight:540.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Euphornin C Chemical Structure

CAS No.: 90052-86-1

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All NO Synthase Isoforms :

In Vitro

Euphornin C (1-10 μM; 24 h) inhibits LPS-induced nitric oxide production in BV-2 microglial cells with an inhibitory rate of 41.23% at 1 μM while maintaining high cell viability, but causes severe cytotoxicity at 10 μM^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 90052-86-1
Molecular Weight 540.64
Formula C₃₁H₄₀O₈
SMILES

C[C@H]1/C=C\C(C)(C)[C@H](OC(C)=O)CC(/C(C)=C/[C@]([C@@H](OC(C2=CC=CC=C2)=O)[C@@H](C)C3)([H])[C@@]3(O)[C@H]1OC(C)=O)=O
Structure Classification
- Terpenoids
- Diterpenoids
Initial Source
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Mai ZP, et al. Heliosterpenoids A and B, two Novel Jatrophane-Derived Diterpenoids with a 5/6/4/6 Ring System from Euphorbia helioscopia. Scientific reports. 2017 Jul 07;7(1):4922.

[2]. Zuo Q, et al. Diterpenoids from the seeds of Euphorbia lathyris and their effects on microglial nitric oxide production. Fitoterapia. 2021 Apr;150:104834.

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References

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Euphornin C

All NO Synthase Isoforms