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Cat. No.: HY-17612A

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Evenamide hydrochloride

(Synonyms: NW-3509 hydrochloride)

Evenamide hydrochloride is an orally available voltage-gated sodium channel (VGSC) blocker (K_i=0.4 μM) for the research of schizophrenia. Evenamide hydrochloride shows efficacy in a broad spectrum of rodent models of psychosis, mania, depression, and aggressiveness.

For research use only. We do not sell to patients.

CAS No.: 1092977-06-4
Formula: C₁₆H₂₇ClN₂O₂
Molecular Weight:314.85

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (263 KB)

Evenamide hydrochloride Chemical Structure

CAS No.: 1092977-06-4

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Fluorescent Dye

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Biological Activity

Description

All Sodium Channel Isoforms :

Chemical Information

CAS No. 1092977-06-4
Molecular Weight 314.85
Formula C₁₆H₂₇ClN₂O₂
SMILES

O=C(CNCCC1=CC=CC(OCCCC)=C1)N(C)C.Cl
Synonyms

NW-3509 hydrochloride
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (263 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Valentina Zuliani, et al. Advances in Design and Development of Sodium Channel Blockers. Ion Channels and Their Inhibitors pp 79-115.

[2]. Faravelli, et al. P.3.f.022 Evenamide (formerly NW-3509) targets new mechanisms, and represents a new approach to the management of untreated symptoms in schizophrenia.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Chemical Information
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References

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Evenamide hydrochloride

All Sodium Channel Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

Evenamide hydrochloride Related Classifications

HY-17612A Related Classifications