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Art. -Nr.: HY-143477

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Factor XI-IN-1

Name: Factor XI-IN-1
Brand: MedChemExpress
SKU: HY-143477
Price: 590.00 USD
Availability: InStock
Rating: 5 (1 reviews)

Factor XI-IN-1 is an activator inhibitor of coagulation factor XI (Factor XI) with an EC₅₀ of 25.14 nM. Factor XI-IN-1 is applicable to research related to thrombosis, embolism, hypercoagulable states and fibrotic changes.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 2720619-72-5
Formel: C₃₀H₃₈N₄O₂
Molecular Weight:486.65

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Factor XI-IN-1 Chemical Structure

CAS. Nr.: 2720619-72-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

EC₅₀: 25.14 nM (Factor XI Activation)^[1]

In Vitro

Factor XI-IN-1 (Compound 27) inhibits FXIIa-mediated activation of human coagulation factor XI, with an EC₅₀ of 25.14 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

CAS. Nr. 2720619-72-5
Molecular Weight 486.65
Formel C₃₀H₃₈N₄O₂
SMILES

N#CC1(C2=CC=CC=C2)CCN(C(C3=NC(C)=C(C)C(C(N4CCC(C(C)(C)C)CC4)=O)=C3)=O)CC1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Sabnis RW, et al. Factor XI Activation Inhibitors for Treating Thromboses, Embolism, Hypercoagulability, or Fibrotic Changes. ACS medicinal chemistry letters. 2022 Oct 13;13(10):1548-1549. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

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MOQ

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100 mg

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