FITC-inulin
FITC-inulin is a FITC (HY-66019)-labeled inulin (Ex/Em=488/525 nm). FITC-inulin serves as an accurate and stable marker for in vivo renal function assessment. FITC-inulin exhibits pH-dependent fluorescence.
For research use only. We do not sell to patients.
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
The fluorescence intensity of FITC-inulin (0-0.8 mg/mL) correlates linearly with its concentration; its fluorescence intensity is pH-dependent, but this can be corrected using HEPES buffer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:NIH-Swiss (male, 30-35 g)[1]
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Dosage:0.75 g/100 mL in isotonic saline (with albumin and glucose)
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Administration:i.v. infusion; 0.25 µl·g body wt-1·min-1; during sample collection
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Result:Showed high correlation with [125I]iothalamate for tubular fluid-to-plasma (TF/P) ratios.
Correlated highly with [125I]iothalamate for whole kidney glomerular filtration rate (GFR).
Exhibited late-proximal TF/P of 1.89, single-nephron GFR (SNGFR) of 9.64 nl/min, and fractional fluid reabsorption of 45.3% before acetazolamide treatment; these values decreased to 1.48, 6.65 nl/min, and 26.8% after acetazolamide treatment.
Maintained stable measurements of TF/P, fluid flow, and SNGFR for at least 2 weeks when stored in the dark at 4°C, with post-storage values nearly identical to initial measurements.
Chemical Information
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Appearance Solid
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Color Light yellow to yellow
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SMILES
[FITC-inulin]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 2 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FITC-inulin Related Classifications
HY-DN7075F Related Classifications
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