FITC-inulin
FITC-inulin is a FITC (HY-66019)-labeled inulin (Ex/Em=488/525 nm). FITC-inulin serves as an accurate and stable marker for in vivo renal function assessment. FITC-inulin exhibits pH-dependent fluorescence.
For research use only. We do not sell to patients.
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Storage:
RT, protect from light.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
The fluorescence intensity of FITC-inulin (0-0.8 mg/mL) correlates linearly with its concentration; its fluorescence intensity is pH-dependent, but this can be corrected using HEPES buffer[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:NIH-Swiss (male, 30-35 g)[1]
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Dosage:0.75 g/100 mL in isotonic saline (with albumin and glucose)
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Administration:i.v. infusion; 0.25 µl·g body wt-1·min-1; during sample collection
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Result:Showed high correlation with [125I]iothalamate for tubular fluid-to-plasma (TF/P) ratios.
Correlated highly with [125I]iothalamate for whole kidney glomerular filtration rate (GFR).
Exhibited late-proximal TF/P of 1.89, single-nephron GFR (SNGFR) of 9.64 nl/min, and fractional fluid reabsorption of 45.3% before acetazolamide treatment; these values decreased to 1.48, 6.65 nl/min, and 26.8% after acetazolamide treatment.
Maintained stable measurements of TF/P, fluid flow, and SNGFR for at least 2 weeks when stored in the dark at 4°C, with post-storage values nearly identical to initial measurements.
Chemical Information
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Appearance Solid
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Color Light yellow to yellow
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SMILES
[FITC-inulin]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
RT, protect from light
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
In Vitro:
DMSO : 50 mg/mL (Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 2 mg/mL (ultrasonic and warming and heat to 60°C)
Purity & Documentation
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Data Sheet (265 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
FITC-inulin Related Classifications
HY-DN7075F Related Classifications
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