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Cat. No.: HY-P0240F

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FITC-Tuftsin

FITC-Tuftsin is a fluorescent probe and a Tuftsin (HY-P0240) receptor ligand that enters macrophages via receptor-mediated internalization, and its uptake is enhanced under Lipopolysaccharides, from E. coli O111:B4 (LPS) (HY-D1056A1)-stimulated macrophage activation. FITC-Tuftsin is used for the study of macrophage-mediated inflammation.

For research use only. We do not sell to patients.

CAS No.: 1373319-09-5
Formula: C₄₈H₆₂N₁₀O₁₂S
Molecular Weight:1003.13

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Custom Peptide Synthesis

FITC-Tuftsin Chemical Structure

CAS No.: 1373319-09-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- In Vitro
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
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Biological Activity

Description

In Vitro

FITC-Tuftsin (0.5-10 μM; 30 min) is internalized/bound by macrophages through the tuftsin receptor mechanism in a concentration-dependent manner, with LPS stimulation augmenting this capture by activated macrophages^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 1373319-09-5
Molecular Weight 1003.13
Formula C₄₈H₆₂N₁₀O₁₂S
Sequence

FITC-Ahx-Thr-Lys-Pro-Arg
Sequence Shortening

FITC-Ahx-TKPR
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Feng J, et al. Tuftsin derivatives of FITC, Tb-DOTA or Gd-DOTA as potential macrophage-specific imaging biomarkers. Contrast media & molecular imaging. 2010;5(4):223-30.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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