Fluocinolone (Standard)
Fluocinolone (Standard) is the analytical standard of Fluocinolone (HY-136642). This product is intended for research and analytical applications. Fluocinolone is a potent steroid with highly selective glucocorticoid receptor agonist activity. Fluocinolone stabilizes the blood-retinal barrier by enhancing endothelial tight junctions, inhibiting the VEGF pathway and inflammatory factors. Fluocinolone has high lipophilicity, enabling long-term sustained release in the vitreous. Fluocinolone is used in research related to dermatological diseases, diabetic macular edema, uveitis and oral lichen planus.
For research use only. We do not sell to patients.
- CAS No.: 807-38-5
- Formula: C21H26F2O6
- Molecular Weight:412.42
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Product Information
The compound is the grade of analytical standard, which is the reference standard supplied assay. It is commonly used in qualitative, quantitative and methodological research experiments in HPLC, GC and MS.
Chemical Information
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CAS No. 807-38-5
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Molecular Weight 412.42
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Formula C21H26F2O6
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SMILES
F[C@]([C@](C1=CC2=O)(C=C2)C)([C@H](C3)O)[C@](C[C@@H]1F)([H])[C@@](C[C@H]4O)([H])[C@]3([C@](O)4C(CO)=O)C
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Aizawa Y, et al. Effects of difluprednate on adrenal cortex and gonadal functions. Folia Pharmacologica Japonica, 1984, 84: 553-561. [Content Brief]
[3]. Jaffe GJ, et al. Fluocinolone acetonide sustained drug delivery device to treat severe uveitis. Ophthalmology. 2000;107(11):2024-2033. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)