Fluridone
Based on 2 publication(s) in Google Scholar
Fluridone is a herbicide, particularly to eliminate aquatic plant growth in water reservoirs and irrigation channels. Fluridone is a potent Abscisic acid (ABA) biosynthesis inhibitor, and has anti-inflammatory effects.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.93%
- CAS No.: 59756-60-4
- 화학식: C19H14F3NO
- 분자량:329.32
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보관:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
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Immunology/Inflammation Compound Library
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Publications Citing Use of MedChemExpress (MCE) Fluridone
More
Biological Activity
Fluridone (0.5-50 μM; for 4 days) inhibits the proliferation of aortic smooth muscle cells and reduces proliferation and cytokine release by human activated lymphocytes. In stimulated human monocytes, Fluridone inhibits COX-2 expression and the release of MCP-1 and prostaglandin-E2. Fluridone also inhibits the release from stimulated human monocytes of abscisic acid[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:Lymphocytes
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Concentration:0.5 μM, 2 μM, 5 μM, 50 μM
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Incubation Time:for 4 days
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Result:Inhibited the proliferation of aortic smooth muscle cells.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Male CD mice (20-22 g) treated with Zymosan[1]
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Dosage:8.25 mg/kg
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Administration:i.p.; once
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Result:Reduced peritoneal inflammation in Zymosan-treated mice.
Chemical Information
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CAS No. 59756-60-4
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Appearance Solid
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분자량 329.32
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화학식 C19H14F3NO
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Color White to off-white
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SMILES
O=C1C(C2=CC=CC=C2)=CN(C)C=C1C3=CC=CC(C(F)(F)F)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (2)
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Journal Impact Factor
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Most Recent
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Cell Rep
RABC1-ABI1 module coordinates lipid droplet mobilization and post-germination growth arrest in Arabidopsis. [Abstract]2025 May 3;44(5):115655. PMID: 40323720 -
Plants
Integrative Analysis of Metabolic Signature and Phytohormone Response in Potato Under Heat, Drought and Salt Stresses. [Abstract]2026 Mar 9;15(5):844. PMID: 41829874
용액&용해도
DMSO : 250 mg/mL (759.14 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (273 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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Handling Instructions (2659 KB)
References
[1]. Mirko Magnone, et al. Fluridone as a new anti-inflammatory drug. Eur J Pharmacol. 2013 Nov 15;720(1-3):7-15. [Content Brief]
[2]. Wei X, et al. MYB41, MYB107, and MYC2 promote ABA-mediated primary fatty alcohol accumulation via activation of AchnFAR in wound suberization in kiwifruit. Hortic Res. 2020;7(1):86. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.0366 mL | 15.1828 mL | 30.3656 mL | 75.9140 mL |
| 5 mM | 0.6073 mL | 3.0366 mL | 6.0731 mL | 15.1828 mL | |
| 10 mM | 0.3037 mL | 1.5183 mL | 3.0366 mL | 7.5914 mL | |
| 15 mM | 0.2024 mL | 1.0122 mL | 2.0244 mL | 5.0609 mL | |
| 20 mM | 0.1518 mL | 0.7591 mL | 1.5183 mL | 3.7957 mL | |
| 25 mM | 0.1215 mL | 0.6073 mL | 1.2146 mL | 3.0366 mL | |
| 30 mM | 0.1012 mL | 0.5061 mL | 1.0122 mL | 2.5305 mL | |
| 40 mM | 0.0759 mL | 0.3796 mL | 0.7591 mL | 1.8979 mL | |
| 50 mM | 0.0607 mL | 0.3037 mL | 0.6073 mL | 1.5183 mL | |
| 60 mM | 0.0506 mL | 0.2530 mL | 0.5061 mL | 1.2652 mL | |
| 80 mM | 0.0380 mL | 0.1898 mL | 0.3796 mL | 0.9489 mL | |
| 100 mM | 0.0304 mL | 0.1518 mL | 0.3037 mL | 0.7591 mL |
Fluridone Related Classifications
HY-134094 Related Classifications
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