Fmoc-PEA
Based on 1 Customer Validation
Fmoc-PEA (Example 1-2) is a used as a cleavable linker for antibody-drug conjugates (ADC).
For research use only. We do not sell to patients.
- Purity: 99.47%
- CAS No.: 329223-23-6
- Formula: C17H18NO6P
- Molecular Weight:363.30
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Storage:
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Biological Activity
|
Phosphatase Cleavable Linker |
Cleavable Linker |
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 329223-23-6
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Appearance Solid
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Molecular Weight 363.30
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Formula C17H18NO6P
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Color White to light yellow
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SMILES
O=C(OCC1C2=C(C3=C1C=CC=C3)C=CC=C2)NCCOP(O)(O)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
4°C, sealed storage, away from moisture and light
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
DMSO : 200 mg/mL (550.51 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.7525 mL | 13.7627 mL | 27.5255 mL | 68.8137 mL |
| 5 mM | 0.5505 mL | 2.7525 mL | 5.5051 mL | 13.7627 mL | |
| 10 mM | 0.2753 mL | 1.3763 mL | 2.7525 mL | 6.8814 mL | |
| 15 mM | 0.1835 mL | 0.9175 mL | 1.8350 mL | 4.5876 mL | |
| 20 mM | 0.1376 mL | 0.6881 mL | 1.3763 mL | 3.4407 mL | |
| 25 mM | 0.1101 mL | 0.5505 mL | 1.1010 mL | 2.7525 mL | |
| 30 mM | 0.0918 mL | 0.4588 mL | 0.9175 mL | 2.2938 mL | |
| 40 mM | 0.0688 mL | 0.3441 mL | 0.6881 mL | 1.7203 mL | |
| 50 mM | 0.0551 mL | 0.2753 mL | 0.5505 mL | 1.3763 mL | |
| 60 mM | 0.0459 mL | 0.2294 mL | 0.4588 mL | 1.1469 mL | |
| 80 mM | 0.0344 mL | 0.1720 mL | 0.3441 mL | 0.8602 mL | |
| 100 mM | 0.0275 mL | 0.1376 mL | 0.2753 mL | 0.6881 mL |