Itriglumide
Itriglumide (CR 2945) is an anthranilic acid derivative. Itriglumide is a potent and selective CCKB receptor antagonist, with an IC50 of 2.3 nM. Itriglumide antagonizes the response to gastrin in a dose-dependent manner with an IC50 of 5.9 nM. Itriglumide shows antisecretory and antiulcer activity.
For research use only. We do not sell to patients.
- CAS No.: 201605-51-8
- Formula: C33H38N2O4
- Molecular Weight:526.67
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
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HY-17617
NastorazepideCCK-2 Receptor Antagonist -
HY-P1097
Gastrin I, humanCCK2 Agonist -
![[Leu15]-Gastrin I (human)](https://file.medchemexpress.com/product_pic/hy-p2671.gif)
HY-P2671
[Leu15]-Gastrin I (human)Peptide Hormone -
HY-17617R
Nastorazepide (Standard)CCK-2 Receptor Antagonist -
HY-103354
Proglumide sodiumCCK-A/B Receptors Antagonist -
HY-101764
LintitriptCCK1 Receptor Antagonist -
HY-B1439B
Lorglumide sodiumCholecystokinin Receptor Antagonist -
HY-162070
CCK antagonist 1CCK Antagonist -
HY-105226
CI-988CCK2R Antagonist -
HY-101764R
Lintitript (Standard)Reference Standard -
HY-B1439BR
Lorglumide sodium (Standard)Cholecystokinin Receptor Antagonist -
HY-103354R
Proglumide sodium (Standard)CCK-A/B Receptors Antagonist
Biological Activity
Description
IC50 & Target
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CCKBR 2.3 nM (IC50) |
Chemical Information
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CAS No. 201605-51-8
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Molecular Weight 526.67
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Formula C33H38N2O4
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SMILES
O=C(C1=C(C(C)=CC(C)=C1)NC(C[C@@H](C2=CC=CC3=CC=CC=C23)CC(O)=O)=O)N4CCC5(CCCC5)CC4
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Synonyms
CR 2945
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Cell Cytotoxicity Assay
Cytotoxicity assays are usually based on the assessment of cell membrane damage, which can also be indirectly detected by measuring cell viability. Detection methods include MTT assay, CKK-8 assay, LDH assay and ATP assay, etc.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Itriglumide Related Classifications
HY-106347 Related Classifications
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