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Panitumumab

(Synonyms: ABX-EGF)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Panitumumab (ABX-EGF) is a fully human IgG2 anti-EGFR monoclonal antibody with anti-tumor activity. Panitumumab inhibits tumor cell proliferation, survival and angiogenesis. Panitumumab can be used in the research of cancers, such as colon cancer.

For research use only. We do not sell to patients.

  • Purity: 99.77%
  • CAS No.: 339177-26-3
  • Molecular Weight:144.32 kDa
  • Storage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Experimental Validation Results for Panitumumab
  • Panitumumab Chemical Structure
    Panitumumab Chemical Structure
CAS No.: 339177-26-3
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609-228-6898
[email protected] [email protected]
Find Your Local Distributor Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG2 kappa

  • 1/16

    Immobilized EGFR Protein, Human can bind Panitumumab. The EC50 for this effect is 47.19 ng/mL.

  • 1/16

    Panitumumab has a significant ADCP effect on CHOK1-human EGFR cells in a dose-dependent manner.The EC50 for this effect is 130.4 ng/mL.

  • 1/16

    Panitumumab purchased from MedChemExpress. Usage Cited in: Sci Rep. 2022 Jul 7;12(1):11561. [Abstract]

    Customer Validation
     HeLa cells were pretreated with 100 nM cetuximab (Cmab) or 30 nM panitumumab (Pmab) for 10 min and then stimulated with 20 ng/mL TNF-α for 15 or 60 min. The expression of the indicated proteins was detected by immunoblotting.

  • 1/16

    Panitumumab purchased from MedChemExpress. Usage Cited in: Sci Rep. 2022 Jul 7;12(1):11561. [Abstract]

    Customer Validation
     Panitumumab (100 nM, 25 min) was internalized upon stimulation with TNF-α (20 ng/mL, 15 min) in HeLa cells.

  • Panitumumab Chemical Structure
    1/16
  • Panitumumab
  • Immobilized EGFR Protein, Human can bind Panitumumab. The EC50 for this effect is 47.19 ng/mL.
  • Panitumumab has a significant ADCP effect on CHOK1-human EGFR cells in a dose-dependent manner.The EC50 for this effect is 130.4 ng/mL.