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Cat. No.: HY-121690

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Semotiadil

Name: Semotiadil
Brand: MedChemExpress
SKU: HY-121690
Price: 569.00 USD
Availability: InStock
Rating: 5 (1 reviews)

(Synonyms: SD-3211)

Semotiadil (SD-3211), a benzothiazine compound, is a Ca²⁺ antagonist. Semotiadil exerts antiplatelet activity.

For research use only. We do not sell to patients.

CAS No.: 116476-13-2
Formula: C₂₉H₃₂N₂O₆S
Molecular Weight:536.64

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

Semotiadil Chemical Structure

CAS No.: 116476-13-2

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Semotiadil (SD-3211), a benzothiazine compound, is a Ca²⁺ antagonist. Semotiadil exerts antiplatelet activity^[1].

All Calcium Channel Isoforms :

Chemical Information

CAS No. 116476-13-2
Molecular Weight 536.64
Formula C₂₉H₃₂N₂O₆S
SMILES

O=C1[C@H](SC2=CC=CC=C2N1C)C3=CC(OC)=CC=C3OCCCN(C)CCOC4=CC=C5OCOC5=C4
Synonyms

SD-3211
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Protocols

All Cell Biology

Ca²⁺ Staining Technique
Ca²⁺ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca²⁺ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wolfram RM, et al. Antiplatelet activity of semotiadil fumarate. Thromb Res. 2002 May 15;106(4-5):187-90. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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