OX01914
OX01914 is a water-solube and permeable utrophin modulator (upregulates utrophin protein levels), with an EC50 of 20.5 μM. OX01914 can be used in study of duchenne muscular dystrophy (DMD).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 49676-35-9
- Formule: C17H14N4O
- Masse moléculaire:290.32
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
Description
In Vitro
OX01914 (0.1, 10, 40, 50 μM; 24 h) upregulates utrophin mRNA in LUmdx and (30 μM; 24 h) H2K mdx myoblasts[1].
OX01914 (1, 3, 30; 24 h) upregulates utrophin protein levels in human DMD muscle cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
-
Cell Line:LUmdx and H2K mdx myoblasts
-
Concentration:0.1, 10, 40, 50 µM (for LUmdx myoblasts) ; 30 µM (for H2K mdx myoblasts).
-
Incubation Time:24 h
-
Result:Upregulated utrophin mRNA both in LUmdx and H2K mdx myoblasts.
-
Cell Line:Human DMD cells
-
Concentration:1, 3, 30 µM
-
Incubation Time:24 h
-
Result:Increased utrophin protein levels by approximately 3-fold.
Chemical Information
-
CAS No. 49676-35-9
-
Masse moléculaire 290.32
-
Formule C17H14N4O
-
SMILES
O=C(NN)C1=NC(C2=CC=CC=C2)=CC(C3=CC=CC=C3)=N1
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
OX01914 Related Classifications
HY-150078 Related Classifications
Powered by Bioz