2. Metabolic Enzyme/Protease
  3. Fat Mass and Obesity-associated Protein (FTO)
  4. FTO-IN-1

FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 can be used for the research of cancer.

At equivalent molar concentrations, both the salt and free forms of a compound exhibit comparable biological activity. Nevertheless, the salt form (FTO-IN-1 TFA) usually boasts enhanced water solubility and stability.

For research use only. We do not sell to patients.

FTO-IN-1 Chemical Structure

FTO-IN-1 Chemical Structure

CAS No. : 2243944-92-3

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Other Forms of FTO-IN-1:

FTO-IN-1 Related Antibodies

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Description

FTO-IN-1 is a fat mass and obesity-associated enzyme (FTO) inhibitor extracted from patent WO2018157843A1, compound 32, with an IC50 of <1 μM. FTO-IN-1 can be used for the research of cancer[1].

IC50 & Target

IC50: <1 μM (FTO)[1]
In Vitro

FTO-IN-1 (50 μM) inhibits FTO enzyme activity by 62% in vitro[1].
FTO-IN-1 (50 μM) inhibits the viability of SCLC-21H, RH30 and KP3 cells, with IC50s of 2.1 μM, 5.3 μM, and 5.6 μM, respectively[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

FTO-IN-1 Related Antibodies
Molecular Weight

391.25

Formula

C18H16Cl2N4O2
CAS No.
SMILES

O=C(NO)C1=CC=CC=C1NC2=C(Cl)C=C(C3=C(C)NN=C3C)C=C2Cl
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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FTO-IN-1 Related Classifications

  • Molarity Calculator

  • Dilution Calculator

The molarity calculator equation

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass   Concentration   Volume   Molecular Weight *
= × ×

The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

FTO-IN-12243944-92-3Fat Mass and Obesity-associated Protein (FTO)fatmassobesityassociatedenzymeFTOcancerInhibitorinhibitorinhibit

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FTO-IN-1
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