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  3. Amino Acid Derivatives
  4. Fudosteine

Fudosteine 

Cat. No.: HY-B0393 Purity: ≥98.0%
COA Handling Instructions

Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression.

For research use only. We do not sell to patients.

Fudosteine Chemical Structure

Fudosteine Chemical Structure

CAS No. : 13189-98-5

Size Price Stock Quantity
Solution
10 mM * 1 mL in Water USD 158 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 158 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 144 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

Fudosteine is a cysteine derivative and a mucoactive agent. Fudosteine inhibits MUC5AC mucin hypersecretion by reducing MUC5AC gene expression[1][2].

In Vitro

Fudosteine (50, 100, 200 mg/kg) decreases the LPS-induced p-ERK1/2 and p-p38 MAPK levels in the rat lungs. The TNF-α-induced increase in MUC5AC mRNA expression is inhibited by pretreatment with 1 mM Fudosteine[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Molecular Weight

179.24

Appearance

Solid

Formula

C6H13NO3S
CAS No.
SMILES

N[[email protected]@H](CSCCCO)C(O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

H2O : ≥ 100 mg/mL (557.91 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 5.5791 mL 27.8956 mL 55.7911 mL
5 mM 1.1158 mL 5.5791 mL 11.1582 mL
10 mM 0.5579 mL 2.7896 mL 5.5791 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 50 mg/mL (278.96 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation

Purity: ≥98.0%

COA (242 KB) HNMR (234 KB)

Handling Instructions (2659 KB)
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

  • Molarity Calculator

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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Keywords:

Fudosteine13189-98-5Amino Acid DerivativesMUC5ACmRNAmucoactivecysteinederivativeInhibitorinhibitorinhibit

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