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  3. G247

G247 

Cat. No.: HY-145416
Handling Instructions

G247 is a specific MsbA inhibitor. G247 acts as a transmembrane domains (TMDs) wedge, symmetrically increasing nucleotide-binding domains (NBDs) separation and preventing conformational transition of MsbA. G247 suppresses ATPase activity by increasing inter-NBD distance.

For research use only. We do not sell to patients.

G247 Chemical Structure

G247 Chemical Structure

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Description

G247 is a specific MsbA inhibitor. G247 acts as a transmembrane domains (TMDs) wedge, symmetrically increasing nucleotide-binding domains (NBDs) separation and preventing conformational transition of MsbA. G247 suppresses ATPase activity by increasing inter-NBD distance[1].

IC50 & Target

MsbA[1]

Molecular Weight

445.31

Formula

C24H19Cl2FO3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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