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Cat. No.: HY-188142

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Gal-PAB

Gal-PAB is a galactose-linker conjugate that can be used for the synthesis of the galactose-modified PROTAC prodrug Gal-ARV-771 (HY-158331). Gal-PAB is applicable to lung cancer research.

For research use only. We do not sell to patients.

CAS No.: 259684-23-6
Formula: C₂₁H₂₆O₁₁
Molecular Weight:454.42

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Gal-PAB Chemical Structure

CAS No.: 259684-23-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

Gal-PAB is a galactose-linker conjugate that can be used for the synthesis of the galactose-modified PROTAC prodrug Gal-ARV-771 (HY-158331). Gal-PAB is applicable to lung cancer research^[1].

Chemical Information

CAS No. 259684-23-6
Molecular Weight 454.42
Formula C₂₁H₂₆O₁₁
SMILES

CC(O[C@@H]1[C@H]([C@@H](O[C@@H]([C@@H]1OC(C)=O)COC(C)=O)OC2=CC=C(C=C2)CO)OC(C)=O)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Handling Instructions (2659 KB)

References

[1]. Chang M, et al. Selective Elimination of Senescent Cancer Cells by Galacto-Modified PROTACs. Journal of medicinal chemistry. 2024 May 09;67(9):7301-7311. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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